Formation of Two 1:1 Chlorogenic Acid: β-cyclodextrin Complexes at pH 5: Spectroscopic, Thermodynamic and Voltammetric study
نویسندگان
چکیده
Complexation of chlorogenic acid (CA) by b-cyclodextrin (b-CD) at mildly acidic pH, was studied by fluorescence spectroscopy, isothermal titration calorimetry (ITC), cyclic voltammetry (CV) and NMR spectroscopy. Thermodynamic parameters (DH°, DS° and K) determined by both fluorescence and ITC, showed that the complexation of CA by b-CD is an enthalpy-driven process. Results show that CA molecule can be complexed through both polyphenolic and quinic acid moiety, leading to the formation of two supramolecular isomers with 1:1 stoichiometry.
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